| No | Hotel | Rooms | Score | |
|---|---|---|---|---|
| 21 |  |
Le Méridien Frankfurt | 300 | 7.80 |
| 22 | |
Lindner Hotel Frankfurt Hochst, part of JdV by Hyatt | 296 | 7.80 |
| 23 | |
Mercure Residenz Frankfurt Messe | 294 | 7.40 |
| 24 | |
Scandic Frankfurt Museumsufer | 293 | 8.50 |
| 25 | |
Mövenpick Hotel Frankfurt City Messe | 287 | 7.70 |
| 26 | |
Dorint Main Taunus Frankfurt/Sulzbach | 280 | 7.70 |
| 27 | |
Motel One Frankfurt Airport | 271 | 8.30 |
| 28 | |
B&B Hotel Frankfurt-Messe | 264 | 7.60 |
| 29 | |
H4 Hotel Frankfurt Messe | 236 | 8.10 |
| 30 | |
Novotel Frankfurt City | 235 | 7.90 |
| 31 | |
ibis Frankfurt Centrum | 228 | 7.20 |
| 32 | |
Leonardo Royal Hotel Frankfurt | 226 | 7.50 |
| 33 | |
Grand Hotel Empire | 224 | 7.00 |
| 34 | |
MOXY Frankfurt East | 220 | 8.20 |
| 35 | |
Hilton Frankfurt Airport | 215 | 8.20 |
| 36 | |
Flemings Selection Hotel Frankfurt-City | 206 | 8.20 |
| 37 | |
Essential by Dorint Frankfurt-Niederrad | 190 | 8.00 |
| 38 | |
Adina Apartment Hotel Frankfurt Westend | 181 | 8.20 |
| 39 | |
Avani Frankfurt City Hotel - previously NH Collection Frankfurt City | 181 | 8.20 |
| 40 | |
Hotel Cult Frankfurt City | 178 | 8.10 |