| No | Hotel | Rooms | Score | |
|---|---|---|---|---|
| 1 |  |
Staybridge Suites Guelph, an IHG Hotel | 120 | 8.10 |
| 2 | |
Hampton Inn & Suites Guelph | 108 | 7.90 |
| 3 | |
Fairfield Inn & Suites by Marriott Guelph | 88 | 7.90 |
| 4 | |
Delta Hotels by Marriott Guelph Conference Centre | 40 | 8.20 |
| 5 | |
Western Hotel & Executive Suites | 18 | 8.60 |
| 6 | |
Super 8 by Wyndham Guelph | 14 | 6.60 |